Antimicrobial Resistance in One Health (AMRiOH)

Growing antibiotic resistant infections and limited discovery of new antibiotic are jeopardizing public health at global scales. To address this rising global threat, a holistic and multisectoral approach (referred to as One Health) is needed because AMR is a common problem for both human and animal. In 2015, the World Health Organization (WHO) developed a Global Action Plan for AMR with one of its strategic objectives being to strengthen knowledge through surveillance and research. My research group is also part of an ambitious initiative that has been launched by the School of Public Health of HKU under the leadership of Professor Keiji Fukuda, who developed the Global Action Plan on AMR at WHO. Our current research projects involve surveillance of resistant bacteria and resistome in neonates, livestock animals, foods, and the environment. The goal is to better understand the development and spread of AMR in the complex ecosystem.

Microbiome in health and diseases (MiHaD)

Studying microbiome is an exciting and rapidly expanding research filed in both humans and animals. In the past decade, the biological relevance of host’s microbiome has become evident. Microbiome is always defined as a complex collection of microorganisms, with their genes and metabolites, colonizing different body niches, and interacts with the host to assist in the nutrients bioconversion and detoxification, promoting immunity, protecting against pathogens, and maintaining health. Findings demonstrated that human microbiome significantly interacts with the nervous system and the lung in addition to its primary functions in the gastrointestinal tract. In fact, increasing evidence has demonstrated that microbiome can be influenced by several factors such as diets, genetics, age, environmental contaminants, and drugs. The disruption of its balance, that is called dysbiosis, can lead to developing many diseases. Research into host-microbiome interaction has changed clinicians’ perspectives about its role in health and diseases. Our microbiome research ranges from studies on the role of microbiome in the developmental origins of health and disease (DOHaD) to studies on the role of microbiota-gut-brain axis in mental health.

Emergence and dissemination of AMR in Hong Kong Travelers

The aim of this study is to apply an epidemiological approach to prospectively study AMR acquisition in healthy Hong Kong travelers, in order to gain insight into the emergence and dissemination of antimicrobial resistance (AMR) and to identify targets for prevention.

We are inviting you to participate in a study related to the association between international travel and antimicrobial resistance.

 

Targets

- Aged 18 or above

- Hong Kong resident (native/non-native) who planned for international travel during December 2018 - October 2019

Procedures

- Complete a questionnaire about your personal and traveling information

- Provide your stool samples before and after traveling

For application, please register in the form below:

 

https://goo.gl/forms/5n798ewaKJEkiRP32

Applicants will be contacted in person, and need to attend a short introduction session after registration.

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